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Luís Filipe Ribeiro de Azevedo
Benardo Manuel de Sousa Pinto
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Suitable for English-speaking students
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[ms_accordion style=”simple” type=”1″ class=”” id=””] [ms_accordion_item title=”Objectives” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
The Health Research aims to respond to issues in clinical medicine and health of populations, contributing to the knowledge and decision making. The issues addressed in this area concern the study of diagnosis, treatment, prognosis, etiology and prevention of the disease and to study the frequency of phenomena and associated entities.
Understanding the fundamentals of scientific methodology and the development of a set of basic skills becomes in this context essential to the achievement of quality research work.
At the end of this curricular unit students should be able to: (1) design a health research project (2) to critically assess the results of health research, particularly in the context of its application to decision making.
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[ms_accordion_item title=”Learning outcomes and competences” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
At the end of this curricular unit students should be able to: (1) design a health research project (2) to critically assess the results of health research, particularly in the context of its application to decision making.
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[ms_accordion_item title=”Working method” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
Presencial
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Not applicable.
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[ms_accordion_item title=”Program” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
Science and Medicine.
A step-by-step guide to Clinical and Health Services Research.
Formulation of the research question.
Study design (Definitions and classification; Experimental studies: Clinical trials; Observational studies; Diagnostic tests studies).
Frequency, association and impact measures.
Precision and validity, random and systematic errors (bias): Precision, reproducibility and reliability; Selection bias; Information bias; Confounding and Effect modification (Interaction); Causal inference, Modern methods and approaches in causal inference – Graphical representations (DAGs), Contrafactual models of causality, Marginal structural models, Propensity scores, Instrumental variables, Mendelian randomization;
Selection of participants (sampling and sample size; bias in selection of participants).
Selection of methods and instruments for data collection (reproducibility and validity of instruments; design and validation of questionnaires; bias in data collection).
Writing a research protocol.
Collecting, processing and analyzing data.
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[ms_accordion_item title=”Teaching methods and learning activities” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
Theoretical and practical classes and titorial orientation.
An e-learning platform will be used to support theoretical and practical classes.
Course evaluation will be based on a practical work and a final theoretical exam, with a weighting of 20% and 80% of the final grade, respectively. The final theoretical exam will cover the theoretical content of the course and will include: (a) closed choice questions, simple and multiple and (b) open questions with short and long answers. The final exam will have a duration of 90 minutes.
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[ms_accordion_item title=”Evaluation Type” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
Distributed evaluation with final exam
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[ms_accordion_item title=”Eligibility for exams” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
Presence in 75% of the classes.
To be approved the student will have to obtain a minimum grade of 9.5 (in a scale 0-20) in the the final grade of the course (80% Final Written Examination + 20% Practical Work).
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[ms_accordion_item title=”Calculation formula of final grade” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
Course evaluation will be based on Practical Work and a Final Written Examination, with a weighting of 20% and 80% of the final grade, respectively. The Final Written Examination will cover the theoretical content of the course and will include: (a) closed choice questions, simple and multiple and (b) open questions with short and long answers. The Final Written Examination will have a duration of 120 minutes.
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[ms_accordion_item title=”Examinations or Special Assignments” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
In this course the students will have to complete a set of practical exercices as part of the practical examination.
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[ms_accordion_item title=”Special assessment (TE, DA, …)” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
Special assessment periods will be allowed for typical cases, including employed students and members of the students’ representatives association.
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[ms_accordion_item title=”Mandatory literature” color=”” background_color=”” close_icon=”” open_icon=”” status=”open”]
Hulley, S.B., Cummings, S.R., Browner, W.S., Grady, D. G., & Newman, T. B; Designing Clinical Research (4th edition). , Lippincott Williams and Wilkins, 2013
Fletcher, R., & Fletcher, S.W. ; Clinical Epidemiology: The Essentials (5th Edition). , Lippincott Williams and Wilkins, 2014
Haynes, R.B., Sackett, D.L., Guyatt, G.H., & Tugwell, P; Clinical epidemiology: how to do clinical practice research (3rd edition), Lippincott Williams & Wilkins, 2006
Lopes, R.D. & Harrington, R. A. ; Understanding Clinical Research., McGraw-Hill Education., 2013
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